What about the increase in intracranial pressure?

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Microgravity-Induced Visual Impairment/Intracranial Pressure (VIIP) is of recent concern at NASA regarding long-duration space missions. Although its exact cause is not known at this time, it is suspected that the low gravity space environment causes a fluid shift to the brain. This causes an increase in the crewmember’s intracranial pressure (ICP) resulting in optic disc edema and globe eye flattening that can cause mild but persistent changes vision. NASA is currently looking at how to address this medical concern.

Medically therapeutic hypothermia has remained a controversial issue in the debate concerning the management of elevated intracranial hypertension. It is not currently recommended as a standard treatment for increased intracranial pressure in any clinical setting. However, recent studies suggest that hypothermia can lower ICP and may improve patient outcomes. Hypothermia also appeared to be effective in lowering ICP after other therapies have failed.